Regulation of scleral fibroblast differentiation by bone morphogenetic protein-2.

نویسندگان

  • Hong-Hui Li
  • Li-Jun Huo
  • Zhen-Ya Gao
  • Feng Zhao
  • Jun-Wen Zeng
چکیده

Bone morphogenesis proteins (BMPs) are multi-functional growth factors. They are expressed in retina, retinal pigment epithelium (RPE) and sclera and serve as a regulator in the growth and development of the eye. This article reviewed the chondrogenic potency of the sclera, biochemical and pathological changes of myopic scleral tissue and the differentiation of chondrogenesis by BMP-2. We proposed the hypothesis that BMP-2 can regulate differentiate of scleral fibroblasts and affect the development of myopia.

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عنوان ژورنال:
  • International journal of ophthalmology

دوره 7 1  شماره 

صفحات  -

تاریخ انتشار 2014